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Tau Secretion: Good and Bad for Neurons

In Alzheimer’s disease (AD), neurofibrillary tangles (NFTs), lesions composed of hyperphosphorylated and aggregated tau, spread from the transentorhinal cortex to the hippocampal formation and neocortex. Growing evidence indicates that tau pathology propagates trans-synaptically, implying that patho...

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Bibliografiske detaljer
Principais autores: Camille Pernègre, Antoine Duquette, Nicole Leclerc
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-06-01
Serier:Frontiers in Neuroscience
Fag:
Online adgang:https://www.frontiersin.org/article/10.3389/fnins.2019.00649/full
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