Genomics and epigenetics guided identification of tissue-specific genomic safe harbors

Abstract Background Genomic safe harbors are regions of the genome that can maintain transgene expression without disrupting the function of host cells. Genomic safe harbors play an increasingly important role in improving the efficiency and safety of genome engineering. However, limited safe harbor...

Descripció completa

Dades bibliogràfiques

Autors principals:	Dewan Shrestha, Aishee Bag, Ruiqiong Wu, Yeting Zhang, Xing Tang, Qian Qi, Jinchuan Xing, Yong Cheng
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-09-01
Col·lecció:	Genome Biology
Matèries:	Genomic safe harbor Genetic engineering Gene therapy Epigenome Chromatin organization Mobile genetic elements
Accés en línia:	https://doi.org/10.1186/s13059-022-02770-3
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!