Smoking-Induced DNA Hydroxymethylation Signature Is Less Pronounced than True DNA Methylation: The Population-Based KORA Fit Cohort

Despite extensive research on 5-methylcytosine (5mC) in relation to smoking, there has been limited exploration into the interaction between smoking and 5-hydroxymethylcytosine (5hmC). In this study, total DNA methylation (5mC+5hmC), true DNA methylation (5mC) and hydroxymethylation (5hmC) levels we...

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Główni autorzy:	Liye Lai, Pamela R. Matías-García, Anja Kretschmer, Christian Gieger, Rory Wilson, Jakob Linseisen, Annette Peters, Melanie Waldenberger
Format:	Artigo
Język:	Inglês
Wydane:	MDPI AG 2024-06-01
Seria:	Biomolecules
Hasła przedmiotowe:	smoking DNA methylation hydroxymethylation differentially methylated positions (DMPs) differentially methylated regions (DMRs) Illumina Infinium Methylation EPIC BeadChip
Dostęp online:	https://www.mdpi.com/2218-273X/14/6/662
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