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Smoking-Induced DNA Hydroxymethylation Signature Is Less Pronounced than True DNA Methylation: The Population-Based KORA Fit Cohort

Despite extensive research on 5-methylcytosine (5mC) in relation to smoking, there has been limited exploration into the interaction between smoking and 5-hydroxymethylcytosine (5hmC). In this study, total DNA methylation (5mC+5hmC), true DNA methylation (5mC) and hydroxymethylation (5hmC) levels we...

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Principais autores: Liye Lai, Pamela R. Matías-García, Anja Kretschmer, Christian Gieger, Rory Wilson, Jakob Linseisen, Annette Peters, Melanie Waldenberger
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-06-01
coleção:Biomolecules
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Acesso em linha:https://www.mdpi.com/2218-273X/14/6/662
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