PTEN enhances the radiosensitivity of melanoma by inhibiting DNA-PKcs
BackgroundThe phosphatase and tensin homolog (PTEN) is a classical tumor-suppressor gene. Its expression deficiency concurrently drives disease progression in approximately 30% of melanomas and is closely associated with radiotherapy tolerance. However, there is a lack of systematic evidence regardi...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2026-01-01
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| Serier: | Frontiers in Cell and Developmental Biology |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1712429/full |
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