NU7441, a selective inhibitor of DNA-PKcs, alleviates intracerebral hemorrhage injury with suppression of ferroptosis in brain

Neuronal apoptosis, oxidative stress, and ferroptosis play a crucial role in the progression of secondary brain injury following intracerebral hemorrhage (ICH). Although studies have highlighted the important functions of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) in various experimen...

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Bibliografski detalji

Glavni autori:	Xiyu Gong, Cuiying Peng, Zhou Zeng
Format:	Artigo
Jezik:	Inglês
Izdano:	PeerJ Inc. 2024-11-01
Serija:	PeerJ
Teme:	DNA-PKcs DNA-PKcs inhibitor (NU7441) Intracerebral hemorrhage Apoptosis Oxidative stress Ferroptosis
Online pristup:	https://peerj.com/articles/18489.pdf
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