NU7441, a selective inhibitor of DNA-PKcs, alleviates intracerebral hemorrhage injury with suppression of ferroptosis in brain

Neuronal apoptosis, oxidative stress, and ferroptosis play a crucial role in the progression of secondary brain injury following intracerebral hemorrhage (ICH). Although studies have highlighted the important functions of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) in various experimen...

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Autors principals:	Xiyu Gong, Cuiying Peng, Zhou Zeng
Format:	Artigo
Idioma:	Inglês
Publicat:	PeerJ Inc. 2024-11-01
Col·lecció:	PeerJ
Matèries:	DNA-PKcs DNA-PKcs inhibitor (NU7441) Intracerebral hemorrhage Apoptosis Oxidative stress Ferroptosis
Accés en línia:	https://peerj.com/articles/18489.pdf
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