MKP-4 suppresses hepatocarcinogenesis by targeting ERK1/2 pathway

Abstract Background Mitogen-activated protein kinase phosphatases-4 (MKP-4) is reported to exert a prognostic merit in hepatocarcinogenesis. However, the underlying molecular mechanisms have not been clearly defined. Methods Immunoprecipitation-mass spectrometry (IP-MS) approach was used to identify...

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Principais autores:	Zhongyi Shen, Chengliang Zhang, Lishuai Qu, Cuihua Lu, Mingbing Xiao, Runzhou Ni, Jinxia Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2019-03-01
Serija:	Cancer Cell International
Teme:	MKP-4 ERK1/2 Hepatocellular carcinoma Phosphorylation Prognosis
Online dostop:	http://link.springer.com/article/10.1186/s12935-019-0776-3
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