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Gubenyiliu II Inhibits Breast Tumor Growth and Metastasis Associated with Decreased Heparanase Expression and Phosphorylation of ERK and AKT Pathways

Gubenyiliu II (GYII), a Traditional Chinese Medicine (TCM) formula used in our hospital, has shown beneficial effects in cancer patients. In this study, we investigated the molecular mechanisms underlying the beneficial effects of GYII on murine breast cancer models. GYII showed significant inhibito...

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Sábháilte in:
Príomhchruthaitheoirí: Yi Zhang, Gan-Lin Zhang, Xu Sun, Ke-Xin Cao, Ya-Wen Shang, Mu-Xin Gong, Cong Ma, Nan Nan, Jin-Ping Li, Ming-Wei Yu, Guo-Wang Yang, Xiao-Min Wang
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2017-05-01
Sraith:Molecules
Ábhair:
Gubenyiliu II
breast tumor
heparanase
growth factors
ERK and AKT pathways
Rochtain ar líne:http://www.mdpi.com/1420-3049/22/5/787
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