Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
Abstract Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections. Here we show that human macrophage phenotypes biosynthesize unique lipid mediator signatures when exposed to pathogenic bacteria. E. coli a...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2018-01-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-017-02538-5 |
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