The Phosphorylation of CCR6 on Distinct Ser/Thr Residues in the Carboxyl Terminus Differentially Regulates Biological Function

CCR6 is a G protein-coupled receptor (GPCR) that recognizes a single chemokine ligand, CCL20 and is primarily expressed by leukocytes. Upon ligand binding, CCR6 activates Gαi heterotrimeric G proteins to induce various potential cellular outcomes through context-specific cell signaling. It is well k...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Mei-Yi Lu, Syuan-Shao Lu, Shiann-Luen Chang, Fang Liao
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2018-03-01
Sarja:	Frontiers in Immunology
Aiheet:	CCR6 G protein-coupled receptor mutagenesis receptor phosphorylation β-arrestins
Linkit:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00415/full
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