Prolonged exposure to teixobactin generates cross-tolerance to other cell wall-targeting antimicrobials in Enterococcus faecalis

ABSTRACT Antimicrobial tolerance, i.e., the ability to survive despite growth inhibition, is an important precursor to the development of antimicrobial resistance. However, very little is known about the evolution of drug-induced antimicrobial tolerance. Teixobactin (TXB) is an antimicrobial peptide...

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主要な著者:	Rachel L. Darnell, Melanie K. Knottenbelt, Olivia E. Rose, Caitlin S. B. Cleary, Francesca O. Todd Rose, Hannah Hodgkinson, Yuezhou Wu, Maytham Hussein, Tony Velkov, Susanne Gebhard, Gregory M. Cook
フォーマット:	Artigo
言語:	Inglês
出版事項:	ASM 2025-12-01
シリーズ:	Antimicrobial Agents and Chemotherapy
主題:	mevalonate pathway cell envelope stress response LiaFSR cross-tolerance Enterococcus cell wall targeting
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/aac.00629-25
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