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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

<p>Abstract</p> <p>Background</p> <p>Mammalian cells have been reported to have a p53-dependent tetraploidy checkpoint that blocks cell cycle progression in G1 in response to failure of cell division. In most cases where the tetraploidy checkpoint has been observed cell division was perturbed by ant...

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书目详细资料
Principais autores: Stearns Tim, Wong Connie
格式: Artigo
语言:Inglês
出版: BMC 2005-02-01
丛编:BMC Cell Biology
在线阅读:http://www.biomedcentral.com/1471-2121/6/6
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