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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

<p>Abstract</p> <p>Background</p> <p>Mammalian cells have been reported to have a p53-dependent tetraploidy checkpoint that blocks cell cycle progression in G1 in response to failure of cell division. In most cases where the tetraploidy checkpoint has been observed cell division was perturbed by ant...

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Hlavní autoři: Stearns Tim, Wong Connie
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2005-02-01
Edice:BMC Cell Biology
On-line přístup:http://www.biomedcentral.com/1471-2121/6/6
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