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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

<p>Abstract</p> <p>Background</p> <p>Mammalian cells have been reported to have a p53-dependent tetraploidy checkpoint that blocks cell cycle progression in G1 in response to failure of cell division. In most cases where the tetraploidy checkpoint has been observed cell division was perturbed by ant...

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Bibliografske podrobnosti
Principais autores: Stearns Tim, Wong Connie
Format: Artigo
Jezik:Inglês
Izdano: BMC 2005-02-01
Serija:BMC Cell Biology
Online dostop:http://www.biomedcentral.com/1471-2121/6/6
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