Chromosomal Instability May Not Be a Predictor for Immune Checkpoint Inhibitors from a Comprehensive Bioinformatics Analysis

Immune checkpoint inhibitors (ICIs) have become the standard of care in various cancers, although their predictive tools have not yet completely developed. Here, we aimed to exam the role of 70-gene chromosomal instability signature (CIN70) in cancers, and its association with previous predictors, t...

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Библиографические подробности

Главные авторы:	Chiao-En Wu, Da-Wei Yeh, Yi-Ru Pan, Wen-Kuan Huang, Ming-Huang Chen, John Wen-Cheng Chang, Jen-Shi Chen, Yu-Chao Wang, Chun-Nan Yeh
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2020-11-01
Серии:	Life
Предметы:	CIN70 chromosomal instability immunotherapy immune checkpoint inhibitors tumor mutation burden microsatellite instability
Online-ссылка:	https://www.mdpi.com/2075-1729/10/11/276
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