Isorhamnetin attenuates diabetic kidney disease by modulating mitochondrial homeostasis and suppressing cGAS-STING axis-dependent NLRP3 inflammasome activation
Objective: To evaluate the effect of isorhamnetin on diabetic kidney disease and elucidate its underlying mechanisms. Methods: A high glucose-stimulated mouse podocyte (MPC-5) model was employed to evaluate the effects of isorhamnetin on podocyte injury, secretion of inflammatory cytokines, NLRP3 in...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wolters Kluwer Medknow Publications
2026-06-01
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| Serija: | Asian Pacific Journal of Tropical Biomedicine |
| Teme: | |
| Online pristup: | https://journals.lww.com/10.4103/apjtb.apjtb_58_26 |
| Oznake: |
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