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Multifunctional nanoagent for enhanced cancer radioimmunotherapy via pyroptosis and cGAS-STING activation

Abstract The immunosuppressive tumor microenvironment (ITME) and inherent radioresistance of tumor cells limit the effectiveness of radioimmunotherapy and exacerbate immune evasion. To address these challenges, PEGylated Azacitidine-loaded and Mn2+-doped calcium carbonate nanoparticles (A@MCP NPs) a...

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Detaylı Bibliyografya
Asıl Yazarlar: Ziting Xu, Yang Gao, Li Zhang, Yingshan Gao, Yushu Liao, Yu Liang, Zhen Yuan, Yingjia Li, Bingxia Zhao, Ge Wen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2025-07-01
Seri Bilgileri:Journal of Nanobiotechnology
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Online Erişim:https://doi.org/10.1186/s12951-025-03608-3
Etiketler: Etiketle
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