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Leveraging the crosstalk between cGAS-STING and pyroptosis by nanomedicine to enhance antitumor immunity

Abstract The cGAS-STING pathway and pyroptosis represent two potent immunostimulatory mechanisms with immense potential for cancer therapy. cGAS-STING activation drives type I interferon production and dendritic cell maturation, while pyroptosis, a form of inflammatory programmed cell death, release...

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Principais autores: Yumin Wang, Jinxia Chen, Xuan Zhang, Zhenhua Ji, Na Zhang, Ning Li, Xiu Zhang, Shuang Zhao, Chunfei Li, Kerui Shi, Erdan Wang, Yuzi Jin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-04-01
coleção:Journal of Nanobiotechnology
Assuntos:
Cancer
Glioma
cGAS-STING
Pyroptosis
Nanomedicine
Acesso em linha:https://doi.org/10.1186/s12951-026-04343-z
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