TXNIP aggravates cardiac fibrosis and dysfunction after myocardial infarction in mice by enhancing the TGFB1/Smad3 pathway and promoting NLRP3 inflammasome activation

Myocardial infarction (MI) results in high mortality. The size of fibrotic scar tissue following MI is an independent predictor of MI outcomes. Thioredoxin-interacting protein (TXNIP) is involved in various fibrotic diseases. Its role in po...

Descripció completa

Dades bibliogràfiques

Autors principals:	Zhang Yan, Wang Jin, Wang Xuejiao, Li Aiyun, Lei Zhandong, Li Dongxue, Xing Dehai, Zhang Yichao, Su Wanzhen, Jiao Xiangying
Format:	Artigo
Idioma:	Inglês
Publicat:	China Science Publishing & Media Ltd. 2023-10-01
Col·lecció:	Acta Biochimica et Biophysica Sinica
Matèries:	cardiac fibrosis cardiac function inflammasome myocardial infarction thioredoxin-interacting protein
Accés en línia:	https://www.sciengine.com/doi/10.3724/abbs.2023150
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!