TXNIP aggravates cardiac fibrosis and dysfunction after myocardial infarction in mice by enhancing the TGFB1/Smad3 pathway and promoting NLRP3 inflammasome activation

Myocardial infarction (MI) results in high mortality. The size of fibrotic scar tissue following MI is an independent predictor of MI outcomes. Thioredoxin-interacting protein (TXNIP) is involved in various fibrotic diseases. Its role in po...

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Bibliografiske detaljer

Principais autores:	Zhang Yan, Wang Jin, Wang Xuejiao, Li Aiyun, Lei Zhandong, Li Dongxue, Xing Dehai, Zhang Yichao, Su Wanzhen, Jiao Xiangying
Format:	Artigo
Sprog:	Inglês
Udgivet:	China Science Publishing & Media Ltd. 2023-10-01
Serier:	Acta Biochimica et Biophysica Sinica
Fag:	cardiac fibrosis cardiac function inflammasome myocardial infarction thioredoxin-interacting protein
Online adgang:	https://www.sciengine.com/doi/10.3724/abbs.2023150
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