Prothrombin prevents fatal T cell–dependent anemia during chronic virus infection of mice
Thrombin promotes the proliferation and function of CD8+ T cells. To test if thrombin prevents exhaustion and sustains antiviral T cell activity during chronic viral infection, we depleted the thrombin-precursor prothrombin to 10% of normal levels in mice prior to infection with the clone 13 strain...
Збережено в:
| Автори: | , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Clinical investigation
2025-02-01
|
| Серія: | JCI Insight |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1172/jci.insight.181063 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|