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Glypican 1 mechanosensing mediates eNOS uncoupling during hydrostatic pulmonary edema

Hydrostatic pulmonary edema is a life-threatening condition caused by an acute increase in pulmonary capillary pressure. The molecular mechanisms whereby hydrostatic pulmonary edema develops are unresolved. The pulmonary endothelial glycocalyx is a mechano-sensitive signaling layer known to regulate...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lakshmi Narasimha Rao Thota, Joaquin Enrique Lopez Rosales, Ayman Isbatan, Christian Bime, Joao Luis Carvalho-de-Souza, Randal O. Dull, Stephen M. Black, Andreia Zago Chignalia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-11-01
Schriftenreihe:Redox Biology
Schlagworte:
Glypican 1
eNOS
Mechanotransduction
Edema
Barrier
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2213231725003891
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