Hepatitis C Virus Proteins Core and NS5A Are Highly Sensitive to Oxidative Stress-Induced Degradation after eIF2α/ATF4 Pathway Activation

Hepatitis C virus (HCV) infection is accompanied by increased oxidative stress and endoplasmic reticulum stress as a consequence of viral replication, production of viral proteins, and pro-inflammatory signals. To overcome the cellular stress, hepatocytes have developed several adaptive mechanisms l...

Description complète

Détails bibliographiques

Auteurs principaux:	W. Alfredo Ríos-Ocampo, María-Cristina Navas, Manon Buist-Homan, Klaas Nico Faber, Toos Daemen, Han Moshage
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2020-04-01
Collection:	Viruses
Sujets:	hepatitis C virus Core NS5A oxidative stress autophagy-adaptor proteins eIF2a/ATF4 pathway
Accès en ligne:	https://www.mdpi.com/1999-4915/12/4/425
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!