Spectrophotometric Investigations of Charge Transfer Complexes of Tyrosine Kinase Inhibitors with Iodine as a σ-Electron Acceptor: Application to Development of Universal High-Throughput Microwell Assay for Their Determination in Pharmaceutical Formulations

<i>Background and Objective</i>: Tyrosine kinase inhibitors (TKIs) are used for the treatment of different types of cancers. The current study describes, for the first time, the ultraviolet-visible spectrophotometric investigation of charge transfer complexes (CTCs) of seven TKIs, as electron donors...

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Principais autores:	Ibrahim A. Darwish, Hany W. Darwish, Awadh M. Ali, Halah S. Almutairi
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2023-04-01
叢編:	Medicina
主題:	tyrosine kinase inhibitors Iodine charge-transfer complex 96-Microwell spectrophotometric assay high-throughput analysis
在線閱讀:	https://www.mdpi.com/1648-9144/59/4/775
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