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Development of Novel Micellar-Enhanced High-Throughput Microwell Spectrofluorimetric Method for Quantification of Lorlatinib: Application to In Vitro Drug Release and Analysis of Urine Samples

Lorlatinib (LOR) is a third-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor drug. The Food and Drug Administration (FDA) has granted an approval for the use of LOR as a first therapeutic intervention for individuals diagnosed with ALK-positive metastatic and advanced non-small-...

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Principais autores: Abdullah M. Al-Hossaini, Hany W. Darwish, Ahmed H. Bakheit, Ibrahim A. Darwish
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-09-01
coleção:Pharmaceuticals
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Acesso em linha:https://www.mdpi.com/1424-8247/16/9/1260
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