Spectrophotometric Investigations of Charge Transfer Complexes of Tyrosine Kinase Inhibitors with Iodine as a σ-Electron Acceptor: Application to Development of Universal High-Throughput Microwell Assay for Their Determination in Pharmaceutical Formulations

<i>Background and Objective</i>: Tyrosine kinase inhibitors (TKIs) are used for the treatment of different types of cancers. The current study describes, for the first time, the ultraviolet-visible spectrophotometric investigation of charge transfer complexes (CTCs) of seven TKIs, as electron donors...

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Principais autores:	Ibrahim A. Darwish, Hany W. Darwish, Awadh M. Ali, Halah S. Almutairi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-04-01
coleção:	Medicina
Assuntos:	tyrosine kinase inhibitors Iodine charge-transfer complex 96-Microwell spectrophotometric assay high-throughput analysis
Acesso em linha:	https://www.mdpi.com/1648-9144/59/4/775
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