FH535-mediated inhibition of Wnt/β-catenin suppresses CRC growth and invasion and alters MCP1 and MCP2 expression with potential immunological implications
BackgroundThe Wnt/β-catenin signaling pathway plays a key role in colorectal cancer (CRC) progression, but its broader biological effects, when blocked, remain poorly understood. In this study, we examined the direct antitumor effects and the impact on the tumor microenvironment of FH535, a small-mo...
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| Huvudupphov: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Frontiers Media S.A.
2026-04-01
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| Serie: | Frontiers in Oncology |
| Ämnen: | |
| Länkar: | https://www.frontiersin.org/articles/10.3389/fonc.2026.1800308/full |
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