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Ezetimibe, Niemann-Pick C1 like 1 inhibitor, modulates hepatic phospholipid metabolism to alleviate fat accumulation

BackgroundEzetimibe, which lowers cholesterol by blocking the intestinal cholesterol transporter Niemann-Pick C1 like 1, is reported to reduce hepatic steatosis in humans and animals. Here, we demonstrate the changes in hepatic metabolites and lipids and explain the underlying mechanism of ezetimibe...

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Detaylı Bibliyografya
Asıl Yazarlar: Hyekyung Yang, Dong Ho Suh, Eun Sung Jung, Yoonjin Lee, Kwang-Hyeon Liu, In-Gu Do, Choong Hwan Lee, Cheol-Young Park
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2024-06-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fphar.2024.1406493/full
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