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Yin Yang 1 intronic binding sequences and splicing elicit intron-mediated enhancement of ubiquitin C gene expression.

In a number of organisms, introns affect expression of the gene in which they are contained. Our previous studies revealed that the 5'-UTR intron of human ubiquitin C (UbC) gene is responsible for the boost of reporter gene expression and is able to bind, in vitro, Yin Yang 1 (YY1) trans-acting fact...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Marzia Bianchi, Rita Crinelli, Elisa Giacomini, Elisa Carloni, Lucia Radici, Mauro Magnani
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3680475?pdf=render
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