Palytoxin and an Ostreopsis toxin extract increase the levels of mRNAs encoding inflammation-related proteins in human macrophages via p38 MAPK and NF-κB.

<h4>Background</h4>Palytoxin and, likely, its analogues produced by the dinoflagellate genus Ostreopsis, represent a class of non-proteinaceous compounds displaying high toxicity in animals. Owing to the wide distribution and the poisonous effects of these toxins in humans, their chemistry and mecha...

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Bibliografische Detailangaben

Hauptverfasser:	Rita Crinelli, Elisa Carloni, Elisa Giacomini, Antonella Penna, Sabrina Dominici, Cecilia Battocchi, Patrizia Ciminiello, Carmela Dell'Aversano, Ernesto Fattorusso, Martino Forino, Luciana Tartaglione, Mauro Magnani
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0038139&type=printable
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