Bora bridges Aurora-A activation and substrate recognition of PLK1
Abstract The activation of PLK1 in late G2 is critical for mitotic entry, requiring its phosphorylation by Aurora-A, facilitated by the intrinsically disordered protein Bora. The structural basis of this mechanism has remained unresolved. Here, we present models of the Aurora-A/Bora complex and the...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Springer Nature
2026-01-01
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| Rangatū: | EMBO Reports |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1038/s44319-025-00687-z |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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