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Ferritinophagy: a possible new iron-related metabolic target in canine osteoblastic osteosarcoma

Canine osteosarcomas (COS) are the most common bone tumors in dogs, characterized by high metastatic rates, poor prognosis, and poor responsiveness to routine therapies, which highlights the need for new treatment targets. In this context, the metabolism of neoplastic cells represents an increasingl...

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Principais autores: Karen Power, Rebecca Leandri, Giorgia Federico, Gionata De Vico, Leonardo Leonardi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-03-01
Serier:Frontiers in Veterinary Science
Fag:
bone cancer
canine osteosarcoma
immunohistochemistry
iron metabolism
therapy
Online adgang:https://www.frontiersin.org/articles/10.3389/fvets.2025.1546872/full
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