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Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle

Abstract Background Causal variants for complex traits, such as eQTL are often found in non-coding regions of the genome, where they are hypothesised to influence phenotypes by regulating gene expression. Many regulatory regions are marked by histone modifications, which can be assayed by chromatin...

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Principais autores: Claire P. Prowse-Wilkins, Thomas J. Lopdell, Ruidong Xiang, Christy J. Vander Jagt, Mathew D. Littlejohn, Amanda J. Chamberlain, Michael E. Goddard
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2022-12-01
Series:BMC Genomics
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Acceso en liña:https://doi.org/10.1186/s12864-022-09002-9
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