Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle

Abstract Background Causal variants for complex traits, such as eQTL are often found in non-coding regions of the genome, where they are hypothesised to influence phenotypes by regulating gene expression. Many regulatory regions are marked by histone modifications, which can be assayed by chromatin...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Claire P. Prowse-Wilkins, Thomas J. Lopdell, Ruidong Xiang, Christy J. Vander Jagt, Mathew D. Littlejohn, Amanda J. Chamberlain, Michael E. Goddard
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2022-12-01
Σειρά:	BMC Genomics
Θέματα:	bovine ChIP-seq histone modifications function causal variants allele specific QTL
Διαθέσιμο Online:	https://doi.org/10.1186/s12864-022-09002-9
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