Wogonoside alleviates hyperosmotic stress-induced inflammation and apoptosis in human corneal epithelial cells via PI3K/AKT signaling

BackgroundDry eye is a multifactorial ocular surface disorder in which tear hyperosmolarity acts as a major stressor that promotes inflammatory injury and apoptosis in corneal epithelial cells. Wogonoside (WGS), a flavonoid glycoside derived from Scutellaria baicalensis, has reported anti-inflammato...

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Hlavní autoři:	Yuan Zhong, Jian Shi, Xi Long, Xiyuan Liu, Lihao Chen, Jun Peng, Qinghua Peng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Medicine
Témata:	dry eye HCE-T cells hyperosmotic stress PI3K/AKT signaling pathway wogonoside
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1828021/full
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