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Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation

Abstract Background Atherosclerosis serves as the fundamental pathology for a variety of cardiovascular disorders, with its pathogenesis being closely tied to the complex interplay among lipid metabolism, oxidative stress, and inflammation. Wogonoside is a natural flavonoid extracted from Scutellari...

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Hlavní autoři: Zhaohui Gong, Haixin Yang, Li Gao, Yi Liu, Qingmin Chu, Chuanjin Luo, Liang Kang, Huiqi Zhai, Qiang Xu, Wei Wu, Nan Li, Rong Li
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-01-01
Edice:BMC Complementary Medicine and Therapies
Témata:
Atherosclerosis
Wogonoside
Inflammation
Network pharmacology
On-line přístup:https://doi.org/10.1186/s12906-025-04760-x
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