Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is among the most prevalent chronic liver diseases worldwide. The expression of YTH domain‐containing protein 1 (YTHDC1) is significantly reduced in patients and mouse models with MASLD. Hepatocyte‐specific knockout of YTHDC1...

Descripció completa

Dades bibliogràfiques

Autors principals:	Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-04-01
Col·lecció:	Advanced Science
Matèries:	lactylation MASLD NLRP3 PTPN22 YTHDC1
Accés en línia:	https://doi.org/10.1002/advs.202510192
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!