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Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity

Summary: Endoplasmic reticulum to mitochondria Ca2+ transfer is important for cancer cell survival, but the role of mitochondrial Ca2+ uptake through the mitochondrial Ca2+ uniporter (MCU) in pancreatic ductal adenocarcinoma (PDAC) is poorly understood. Here, we show that increased MCU expression is...

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Asıl Yazarlar: Jillian S. Weissenrieder, Jessica Peura, Usha Paudel, Nikita Bhalerao, Natalie Weinmann, Calvin Johnson, Maximilian Wengyn, Rebecca Drager, Emma Elizabeth Furth, Karl Simin, Marcus Ruscetti, Ben Z. Stanger, Anil K. Rustgi, Jason R. Pitarresi, J. Kevin Foskett
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2025-05-01
Seri Bilgileri:Cell Reports
Konular:
CP: Cancer
CP: Metabolism
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2211124725003985
Etiketler: Etiketle
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