Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Actin filaments form the backbone of dendritic spines, the postsynaptic compartment of most excitatory synapses in the brain. Spine density changes affect brain function, and postsynaptic actin defects have been implicated in various neuropathies. It is mandatory to identify the actin regulators tha...

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Principais autores:	A. Özge Sungur, Caroline Zeitouny, Lea Gabele, Isabell Metz, Markus Wöhr, Kristin Michaelsen-Preusse, Marco B. Rust
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-08-01
coleção:	Frontiers in Molecular Neuroscience
Assuntos:	actin dynamics spine morphology memory formation social recognition object recognition ultrasonic vocalization
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.952782/full
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