Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4⁺ and CD8⁺T Lymphocytes in Clear Cell Renal Cell Carcinoma

Immunotherapy has shown promising clinical results in clear cell renal cell carcinoma (ccRCC), but low clinical target response rates due to dysfunction of the major histocompatibility complex (MHC) and an inhibitory tumor immune microenvironment (TIME) have largely limited the associated clinical b...

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Ngā kaituhi matua:	Bowen Wang, Yiwen Liu, Feng Xiong, Chunyang Wang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2024-05-01
Rangatū:	Pharmaceuticals
Ngā marau:	cuproptosis human leukocyte antigen tumor-specific major histocompatibility complex-II-II clear cell renal cell carcinoma immunotherapy immune checkpoint inhibitors
Urunga tuihono:	https://www.mdpi.com/1424-8247/17/6/678
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!