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Opposing roles of deubiquitinases in the regulation of IRF7 transcriptional activity

ABSTRACT Virus infection rapidly induces the production and secretion of interferons (IFNs), which amplify the antiviral responses in infected and neighboring uninfected cells. IFN regulatory factor 7 (IRF7), the “master transcription factor,” is pivotal in IFN induction, particularly in myeloid cel...

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Hlavní autoři: Shumin Fan, Pracheta Sengupta, Karan Chawla, Manoj Veleeparambil, Ritu Chakravarti, Saurabh Chattopadhyay
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2026-07-01
Edice:mBio
Témata:
On-line přístup:https://journals.asm.org/doi/10.1128/mbio.02820-25
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