Opposing roles of deubiquitinases in the regulation of IRF7 transcriptional activity
ABSTRACT Virus infection rapidly induces the production and secretion of interferons (IFNs), which amplify the antiviral responses in infected and neighboring uninfected cells. IFN regulatory factor 7 (IRF7), the “master transcription factor,” is pivotal in IFN induction, particularly in myeloid cel...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2026-07-01
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| coleção: | mBio |
| Assuntos: | |
| Acesso em linha: | https://journals.asm.org/doi/10.1128/mbio.02820-25 |
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