Pursing Quinoline-8-Sulfonamide derivatives for the identification of potent NPPs inhibitors: In silico molecular docking, molecular dynamics simulations and density field theory (DFT) studies

Nucleotide pyrophosphatase/phosphodiesterase (NPP) enzymes belong to a broad category of ectonucleotidase enzymes. These NPPs are responsible for hydrolysis of extracellular nucleotides (ATP to AMP) and are therefore important regulators in the purinergic cell signalling. Aberrant expression of NPP...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Jamshed Iqbal, Talha Islam, Mariya al-Rashida, Abdul Hameed, Taseer Iftikhar, Julie Pelletier, Jean Sévigny, Salman Alrokayan, Maria Maqbool, Khurshid Ayub, Tajamul Hussain
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2025-09-01
Saila:	Results in Chemistry
Gaiak:	Ectonucleotidase inhibitors Enzyme assay P-nitrophenyl 5′-thymidine monophosphate NPP1 NPP3 NPPs inhibitors
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2211715625005399
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!