RANTES/CCL5 Induces Collagen Degradation by Activating MMP-1 and MMP-13 Expression in Human Rheumatoid Arthritis Synovial Fibroblasts

Regulated on activation, normal T expressed, and secreted (RANTES)/CC ligand 5 (CCL5) participates in rheumatoid arthritis (RA) pathogenesis by facilitating leukocyte infiltration, however, its other pathological functions are not fully defined in RA. In the present study, we evaluated the effect of...

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Bibliografski detalji

Glavni autori:	Solomon A. Agere, Nahid Akhtar, Jeffery M. Watson, Salahuddin Ahmed
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2017-10-01
Serija:	Frontiers in Immunology
Teme:	rheumatoid arthritis synovial fibroblasts regulated on activation normal T expressed secreted/CC ligand 5 matrix metalloproteinases
Online pristup:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01341/full
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