A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors

Hematopoietic stem cell and multipotent progenitor (MPP) commitment can be tuned in response to an infection so that their differentiation is biased toward myeloid cells. Here, we find that Bach2, which inhibits myeloid differentiation in common lymphoid progenitors, represses a cohort of myeloid ge...

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Autori principali:	Ari Itoh-Nakadai, Mitsuyo Matsumoto, Hiroki Kato, Junichi Sasaki, Yukihiro Uehara, Yuki Sato, Risa Ebina-Shibuya, Mizuho Morooka, Ryo Funayama, Keiko Nakayama, Kyoko Ochiai, Akihiko Muto, Kazuhiko Igarashi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2017-03-01
Serie:	Cell Reports
Soggetti:	B cells gene regulatory network infection multipotent progenitors stem cells super enhancers transcription factors lineage commitment inner myeloid
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124717302103
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