Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

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Bibliografiske detaljer

Principais autores:	Taejin Kim, Mathias Viard, Kirill A. Afonin, Kshitij Gupta, Mary Popov, Jacqueline Salotti, Peter F. Johnson, Charles Linder, Eliahu Heldman, Bruce A. Shapiro
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2020-06-01
Serier:	Molecular Therapy: Nucleic Acids
Fag:	Bolaamphiphiles Vesicles Delivery Systems siRNA Targeting Blood Brain Barrier (BBB)
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2162253120300883
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