Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Taejin Kim, Mathias Viard, Kirill A. Afonin, Kshitij Gupta, Mary Popov, Jacqueline Salotti, Peter F. Johnson, Charles Linder, Eliahu Heldman, Bruce A. Shapiro
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2020-06-01
Σειρά:	Molecular Therapy: Nucleic Acids
Θέματα:	Bolaamphiphiles Vesicles Delivery Systems siRNA Targeting Blood Brain Barrier (BBB)
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2162253120300883
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