Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Taejin Kim, Mathias Viard, Kirill A. Afonin, Kshitij Gupta, Mary Popov, Jacqueline Salotti, Peter F. Johnson, Charles Linder, Eliahu Heldman, Bruce A. Shapiro
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2020-06-01
Sarja:	Molecular Therapy: Nucleic Acids
Aiheet:	Bolaamphiphiles Vesicles Delivery Systems siRNA Targeting Blood Brain Barrier (BBB)
Linkit:	http://www.sciencedirect.com/science/article/pii/S2162253120300883
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!