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Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors

A novel series of ciprofloxacin hybrids comprising various heterocycle derivatives has been synthesized and structurally elucidated using <sup>1</sup>H NMR, <sup>13</sup>C NMR, and elementary analyses. Using ciprofloxacin as a reference, compounds <b>1–21</b> were screened in vitro against Gram-posi...

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Bibliografski detalji
Glavni autori: Lamya H. Al-Wahaibi, Amer A. Amer, Adel A. Marzouk, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Antar A. Abdelhamid
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2021-04-01
Serija:Pharmaceuticals
Teme:
Online pristup:https://www.mdpi.com/1424-8247/14/5/399
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